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Lecture_K - Citric Acid Cycle Part II Learning Objectives...

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Citric Acid Cycle. Part II • Regulation of the citric acid cycle • Eight reactions and eight enzymes of the citric acid cycle •ATP energy equivalent released in glucose catabolism • Metabolic reactions related to the citric acid cycle Learning Objectives
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1. Citrate Synthase COO - C=O CH 2 COO - HO-C-COO - COO - CH 2 CH 2 COO - Oxaloacetate Citrate + CH 3 -C(O)-S-CoA Acetyl-CoA H 2 O HS-CoA • Catalyzes the condensation of Acetyl- CoA and oxaloacetate • The initial reaction of the citric acid cycle • Carbon atoms from carbohydrates, fatty acids, and amino acids enter the cycle in the form of acetyl group attached to CoA. G 0' -32 kJ/mol
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