Chapter 5 - c Facilitated Diffusion i Channels 1 Gated...

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Chapter 5: The Dynamic Cell Membrane I. Bilayer a. 25% is cholesterol II. Proteins a. Proteins and lipids interact only NON-COVALENTLY b. Integral proteins i. Have hydrophobic regions so can span entire bilayer c. Peripheral Proteins i. Lack hydrophobic region so only stick out at one end (inside or outside) III. Carbohydrates a. Cell recognition b. Glycolipids i. Outside membrane – cell recognition 1. Change when cell is cancerous c. Glycoproteins i. Small chains – allow cell to be recognized by other cells IV.Passive Transport (no energy) a. Down a concentration gradient i. High to low b. Simple Diffusion i. Through the membrane ii. Osmosis – diffusion of water 1. Hypertonic – solution has higher solute concentration than compared solution (cell will crenate) 2. Hypotonic – solution has lower solute concentration than cell (cell will lyse) 3. Isotonic – equal solute concentrations
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Unformatted text preview: c. Facilitated Diffusion i. Channels 1. Gated Channel – open and close due to signal which changes shape of protein 2. Ligand-gated – binding of chemical signal 3. Voltage-gated – electrical charge due to ion imbalance a. Direction and pace of ion movement i. Concentration gradient ii. Electrochemical gradient ii. Carrier Proteins 1. Substance binds to membrane protein 2. Polar molecules 3. Saturation point – when all carrier proteins are being used V. Active Transport a. Primary Active Transport i. ATP directly participates b. Secondary Active Transport i. Use energy from ion gradient created by primary c. Uniports i. One substance in one direction d. Symports i. Two substances in same direction e. Antiports i. Two substances in opposite directions 1. Sodium Potassium pump...
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This note was uploaded on 01/27/2011 for the course BIOSC 0150 taught by Professor Lydiadaniels during the Fall '08 term at Pittsburgh.

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Chapter 5 - c Facilitated Diffusion i Channels 1 Gated...

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