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BISC%20300.Chap.07.NOTES

BISC%20300.Chap.07.NOTES - NEED TO BE SPECIFIC TO THE...

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BISC 300 Chapter 7 Notes Control of Microbial Growth 7.1 HISTORICAL PERSPECTIVE 7.2 PHYSICAL METHODS OF CONTROL Heat sterilization and Pasteurization Fig. 7.1 Effect of temperature on survival Fig. 7.2 Decimal reduction times Table 7.1 Heat resistance of bacterial endospores Fig. 7.3 Autoclave Sterilization by radiation Fig. 7.4 The electromagnetic spectrum Sterilization by filtration Fig. 7.5 SEM of filters 7.3 CHEMICAL METHODS OF CONTROL Table 7.2 Common antimicrobial agents Fig. 7.7 Disinfectant/antiseptic compounds Table 7.3 Chemical agents and targets Fig. 7.8 Dilution series for MIC Table 7.4 Modes of action of antimicrobials 7.4 BIOLOGICAL METHODS OF CONTROL IMPORTANT PARADIDM:
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Unformatted text preview: NEED TO BE SPECIFIC TO THE PATHOGENS, BUT NOT HARM THE HUMAN Fig. 7.9 Sulfa drugs Table 7.5 Several antibiotics Box 7.1 The antiobiotic age FIG. 7.11 Antibiotics Resistance to antibiotics Natural resistance: lacks the structure, impermeable Acquired resistance: produces inactivating substance, mutation of target, pumps Common antibiotics and targets: Cell wall: Penicillins ( β-lactams), cephalosporins, vancomycin DNA gyrase: Nalidixic acid, Novobiocin RNA polymerase: Rifampin 50S subunit: Erythromycin, 30S subunit: s, kanamycin (amino glycosides), streptomycin, gentamycin Folic acid metabolism: Trimethoprim, sulfonamides...
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