ProbSet8_solutions(3) - Chapter 10: Chemical Potential and...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
Chapter 10: Chemical Potential and the Drive to Equilibrium (was Ch 11) True/False and Multiple Choice (7) 1) Molecules move spontaneously from regions of low chemical potential to regions of high concentration True/ False 2) The difference in chemical potential for a region with 500mM of molecule B and a region with 1M of molecule B is equal to: a. k b Tln(0.5) b. 0 c. 1 d. k b Tln(500) e. k b Tln(1) 3) The pH of pure water at standard state is: a. Equal to 14 b. Always less than -7 c. the square root of the ion product d. 10 7 e. 81kJmol -1 4) The melting temperature (T m ) is the temperature at which 100% of the protein molecules are unfolded True/ False 5) Which of the following must be independent of temperature when properly applying the van’t Hoff equation: a. K eq b. S o c. 1/T d. pH 6) The pK a of a protein side chain is only dependent on the chemical identity of the side chain not on the surrounding environment.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
True/ False 7) During protein folding, the entropy of water: a. Increases b. Decreases c. Is equal to the protein entropy change d. is 0 Fill in the blank (5) 1) A region with a high chemical potential for molecule A has a _______ concentration of molecular A than a region with low chemical potential. (greater/higher) 2) To make a buffer, add a weak acid to its conjugate _______. (base) 3) _____,______, and ______ side chains generally have a pK a less than 7.0. _______, ________, and ______ side chains have a pK a greater than 9. (His, Asp, Glu and Tyr,Lys,Arg) 4) The integral of the melting curve of heat capacity versus temperature yields the _____________ change of protein unfolding. (enthalpy) 5) The _______________ change for a reaction determines the direction of spontaneous change (free energy or G) Quantitative Problems (12) 1) Two regions of an ideal dilute solution have a difference in concentration of potassium ions (K + ) molecules. At 293K, what is the difference in chemical potential between region 1, with a concentration of 0.5M K + , and region 2, which a concentration of 2mM. Answer: Δ μ = RT ln C 1 C 2 = 8.314 JK 1 mol 1 *293 K *ln 0.5 M 0.002 M = 13450.3 J
Background image of page 2
2) The difference in chemical potential between two regions of an ideal dilute solution is 5kJ. The region with the higher chemical potential has a concentration of 200mM. What is the concentration of the molecule in the other region at 293K? Answer:
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/27/2011 for the course MCB 100A taught by Professor Kuryian during the Spring '09 term at University of California, Berkeley.

Page1 / 12

ProbSet8_solutions(3) - Chapter 10: Chemical Potential and...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online