3_printout - Announcements / review Lecture 3 Remember:...

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Announcements / review Lecture 3 Remember: Keep current with the textbook reading (see syllabus). Reading for today: pages 82-94, 102-106 Reading for tomorrow: pages 113-115, 132-134 Assigned problems: N&C: Ch. 3: #7 SG: p. 33: #8, 12 Yesterday: pKa Amino acids (the “toolbox”) Today: The peptide bond Proteins – what they are and how they are studied Primary sequence
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The peptide bond is made via a dehydration reaction -O - H + A “peptide”:
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Peptides: typically Polypeptides: typically Proteins are Each amino acid within a peptide/polypeptide/protein is often called a “residue” Convention: Peptide and protein sequences begin with Amino (“ N ”) terminus and end with Carboxylate (“ C ”) terminus. 1 2 3 4 5 N C
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We will cover each of these more in-depth later, but for now: Primary (1 0 ) structure: MSEQNSVVNAEKGDGEISSNVETASSVNP…. . Secondary (2 0 ) structure: Tertiary (3 0 ) structure: The arrangement of: Quaternary (4 0 ) structure: The arrangement of: There are four levels of protein structure
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Want to study a protein experimentally?
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3_printout - Announcements / review Lecture 3 Remember:...

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