lecture17 - 20-1Amino Acid CatabolismAmino Acid...

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Unformatted text preview: 20-1Amino Acid CatabolismAmino Acid CatabolismFirst step is removal of the -amino groupby transaminationit is transferred to -ketoglutarateto give glutamateand an -ketoacidThe breakdown of carbon skeletons follows two pathways, depending on the type of endproductglucogenic amino acid:glucogenic amino acid:one whose carbon skeleton is degraded to pyruvateor oxaloacetate, both of which may then be converted to glucose or go into TCA cycleketogenic amino acid:ketogenic amino acid:one whose carbon skeleton is degraded to acetyl-CoAor acetoacetyl-CoA, both of which may then be converted to ketone bodies or go into TCA cycle20-2Amino Acid CatabolismAmino Acid CatabolismGlucogenicAspartateAsparagineAlanineGlycineSerineThreonineCysteineGlutamateGlutamineArginineProlineHistidineValineMethionineKetogenicLeucineLysineGlucogenic and KetogenicIsoleucinePhenylalanineTryptophanTyrosineoff to gluconeogenesisORTCA cycleoff to TCA cycle20-3Amino Acid CatabolismAmino Acid Catabolism...
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lecture17 - 20-1Amino Acid CatabolismAmino Acid...

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