BWn - The threat of bioterrorism People who support or...

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The threat of bioterrorism People who support or participate in bioterrorism are generally fanatics The one might opt to use BW to create terror Biological agents are difficult to detect Many biological agents that Many biological agents that might be weaponized have a delayed onset of effects might be weaponized have a delayed onset of effects Biological weapons BW are defined as: Microorganisms Biologically derived bioactive substances (BDBS) Used to kill or incapacitate people, and to destroy or eliminate food and water supply Characteristics of militarized biological factors: Pathogenic for human, animals or plants The pathogen must be effective- as infectious and as lethal as possible Efficiently dispersible, usually in the air ( based on pathogens acquired through inhalation) Easy and safe to produce (as the pathogen will be required in large amounts) Stable in storage as well as during logistic operations Do not respond to conventional medical treatment Advantages of BW Can multiply and mutate Recombinant technology can be use to make the pathogen more virulent or make a toxin more deadly Are capable of surviving for long periods of time Cultivation utilize common lab equipment and cost far less than conventional armaments Classification of BW Category A agents - most likely to be weaponized - pose the highest potential health risk to the greatest number of people Category B agents - less easy to disseminate - are likely to cause only moderate morbidity and low mortality Category C agents - emerging pathogens that have the potential for mass dissemination W.H.O. Agent Risk Group Classification The term " containment " is used in describing safe methods for managing biohazardous agents in the environment where they are being handled or maintained. Primary containment, the protection of personnel and the immediate laboratory environment from exposure, is provided by good technique and the use of appropriate safety equipment. Secondary containment, the protection of the environment external to the laboratory from exposure to biohazardous agents, is provided by a combination of facility design and operational practices. The four biosafety levels for containment
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purposes and the types of agents placed in them are: BL-1 Biosafety Level 1 – suitable for work involving well-characterized agents of no known or of minimal potential hazard to laboratory personnel and the environment. The laboratory is not necessarily separated from the general traffic patterns in the building. Work is generally conducted on open bench tops using standard microbiological practices. Special containment equipment is not required or generally used. This is the type of laboratory found in municipal water-testing laboratories, in high schools, and in some community colleges. BL-2 Biosafety Level 2 – suitable for work involving
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This note was uploaded on 01/29/2011 for the course MEDICAL 101 taught by Professor Macdon during the Spring '10 term at Mahidol University, Bangkok.

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BWn - The threat of bioterrorism People who support or...

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