Biochemistry Powerpoints

Biochemistry Powerpoints - Metabolism: Basic Concepts and...

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2/4/11 Metabolism: Basic Concepts and Design Metabolism – describes a series of events that include: 1. Obtaining energy and reducing power from exogenous sources. 2. Using that energy to synthesize the basic building blocks necessary for assembly of macromolecules, and ultimately life.
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2/4/11
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2/4/11 Complex? These two basic tasks are highly interconnected and intergraded. Over 1000 chemical reactions take place in simple organisms like E. Coli. These reactions enable movement (muscle contraction/swimming) active transport of molecules and ions Synthesis of macromolecules
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2/4/11 Simple? Many common motifs Use of an energy currency What is the most common energy currency? A group of 100 molecules play key roles in metabolism throughout all life.
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2/4/11 ATP – the universal currency of free energy
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2/4/11 Energy is neither created nor destroyed. It can be converted from one form to another. Phototrophs – use the energy of sunlight and convert it complex energy-rich biomolecules that serve as fuels Chemotrophs – obtain chemical energy through the oxidation of the
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2/4/11 Metabolism is interdependent and interconnected Metabolism consists of many different pathways. Pathways are tightly controlled (allosteric regulation). Two main classes: 1. Catabolic reactions convert energy into biologically useful forms
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2/4/11 Thermodynamics Thermo Terms: H: Enthalpy (heat content) S: Entropy G: Gibbs’ Free Energy G = H – T S
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Why Study Thermodynamics of A Reaction? Or a Pathway? Knowledge of the energy change in a biochemical process allows us to determine whether a reaction will proceed in a test tube or in a living cell and how much work it can theoretically perform . Negative G a reaction is not spontaneous.
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This note was uploaded on 02/03/2011 for the course CHEM 3500 taught by Professor Staff during the Spring '08 term at Kennesaw.

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Biochemistry Powerpoints - Metabolism: Basic Concepts and...

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