Chapter 42 - C hapter 42 Oxygen Oxygen is carried by...

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Chapter 42 Oxygen Oxygen is carried by hemoglobin in the blood; O 2 unloaded from hemoglobin during normal metabolism; O 2 reserve that can be unloaded from hemoglobin to tissues with high metabolism; binding curve – heme molecule binds to oxygen molecules; it takes more oxygen in normal metabolism; partial pressure is lower then the air; bind most of the oxygen before getting in the max oxygen level; the rate is depended upon gradient; the faster the gradient, the most binding sites will occur; binding curve is not fixed, it is subject to chemical that hemoglobin is exposed to; number of factors can shift the curve: pH (the hydrogen ion concentration in blood); as pH goes down, binding curves moves to the right (diffusion of oxygen, nice thing for the tissues); Bohr shift: additional O 2 released from hemoglobin at lower pH (higher O 2 ), a dynamic process; Carbon dioxide Carried in 3 ways: Dissolved (7%) Binds hemoglobin (23%) HCO 3 - (70%) Carbonic anhydrase (enzyme) found within the red blood cells and speed up the reaction between CO 2 and water, a equilibrium process; hydrogen ion lower in blood pH;
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Chapter 42 - C hapter 42 Oxygen Oxygen is carried by...

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