7 - Membrane Structure and Function

7 - Membrane Structure and Function - 7: Membrane Structure...

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7: Membrane Structure and Function 02:43 Overview: Life at the Edge Selective Permeability: the allowance of some substances to cross it more easily than others Importance highlighted when 2003 Nobel Prize in Chemistry awarded to Peter Agre 7.1: Cellular membranes are fluid mosaics of lipids and proteins Phospholipids o Most abundant o Form membranes (inherent ability) o Amphipathic molecule: both a hydrophilic region & a hydrophobic region o Arrangement Fluid mosaic model: the membrane is a fluid structure with a “mosaic” of various proteins embedded in or attached to a double layer (bilayer) Membrane Models: Scientific Inquiry o Begin with electron microscope in 1950s o 1915, red blood cells’ membranes isolated found lipids + proteins o Phospholipid bilayer Stable boundary b/w 2 aqueous compartments b/c molecular arrangement shelters hydrophobic tails of the phospholipids from water Pure phospholipid surface adheres less strongly to water than surface of a biological membrane
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7 - Membrane Structure and Function - 7: Membrane Structure...

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