Genetics380_Exam2_2009_Test1

Genetics380_Exam2_2009_Test1 - Genetics 380 Test #1 NAME _...

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Genetics 380 Test #1 NAME ___________________________________________________ Section or TA name (1 BONUS POINT) _______________________________ 447:380 Genetics November 12, 2009 Professor Maureen Barr EXAM 2: TEST# 1 General Instructions: There are 38 questions on this examination. Please be sure that you have the entire exam (10 pages). Fill in your name and recitation information in the spaces provided. Questions should be answered on the exam. The points on this exam total 102. NOTE: This exam is designed to ascertain what you know about the material. Cheating will not be tolerated. Please keep your eyes on your own paper. Please keep your exam in front of your body, not off to the side. SOME USEFUL INFORMATION ***REGRADING POLICY: All exam regrading requests must be made during the recitation time in which the exams are returned. Your TA will collect your exam, consider your request, and regrade the entire exam, which may result in a higher or lower score. There will be no regrading after the exam is removed from recitation section and from your TAs custody.*** 1
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Genetics 380 Test #1 PART I. MULTIPLE CHOICE answered on exam (48 pts) 1. Which of the following is NOT an example of a single nucleotide polymorphism? A. Silent SNP within a gene B. a microsatellite C. restriction fragment length polymorphism D. chromosomal translocation E. B and D 2. Which of the following statements is FALSE? A. Loci that are far apart have a higher recombination rate than loci that are close together. B. Genetic map distances are based on direct analysis of DNA, whereas physical map distances are based on recombination frequencies. C. People differ, not only at millions of individual SNPs, but also in the number and sizes of repetitive DNA segments of the genome. D. A haplotype is a chromosomal segment defined by the specific array of SNP alleles it carries. E. B and D 3. Which of the following statements is FALSE? A. Ribose sugars have a hydroxyl on the 2′ carbon. B. Frederick Griffith demonstrated that a transforming chemical from dead bacteria could change the genetic information of living bacteria. C. When in an electrical field, DNA will travel toward the anode (positively charged electrode) because DNA is negatively charged. D. All organisms contain DNA that is roughly 25% A, 25% T, 25% G, and 25% C E. Phosphodiester bonds connect nucleotides in a strand; hydrogen bonds hold strands into a double-stranded structure. 4. Which of the following statements is FALSE? A. DNA synthesis during replication is initiated from RNA primers. B. Both eukaryotes and prokaryotes typically have only one origin of replication. C. DNA ligase forms covalent phosphodiester bonds between adjacent nucleotides. D. Okazaki fragments are involved in both lagging and leading DNA strand synthesis.
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This note was uploaded on 01/31/2011 for the course GENETICS 380 taught by Professor Glodowski during the Spring '08 term at Rutgers.

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Genetics380_Exam2_2009_Test1 - Genetics 380 Test #1 NAME _...

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