Unformatted text preview: Label the selectivity filter, central cavity, and the arrangement of transmembrane segments. 9. How does this channel flux K ions at a rapid rate (what is the rate?) while maintaining such a high level of ion selectivity? 10. What is meant by rectification? Draw a current-voltage plot showing the characteristic behavior of an inward rectifying channel. 11. What is meant by primary vs. secondary transport? How does this terminology relate to pumps and transporters? 12. Describe the forces driving movement of ions through ion channels, ion pumps (ATPases), and ion transporters (exchangers, antiporters, symporters). 13. What property of the Na/K pump makes it electrogenic? 14. How does the Na/Ca exchanger extrude Ca from the cytoplasm? What could cause this exchanger to “run in reverse”? Can all exchangers run in reverse? 15. Write the equation for the reversal potential (V r ) of Na-Ca exchanger. 16. Why is the lumen of synaptic vesicles so acidic?...
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- Winter '10
- Ion channel, Muscarinic acetylcholine receptor, Nicotinic acetylcholine receptor, Acetylcholine receptor