lecture 4 - Symport and Antiport Coupled transportation...

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– Coupled transportation – Gradient of one molecule provides energy to transport another – The transporter proteins have two solute- binding sites – one for the driving molecule and another for the co-transported molecule Symport: Gradient of pumps in the same direction Antiport: Gradient of pumps in the opposite direction Symport and Antiport
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• Move materials AGAINST gradient • Highly selective • Requires cellular energy – ATP Nutrient Uptake – Active Transport
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ABC Transporters A TP- B inding C assette Three components : • periplasmic solute- binding protein (SBP) – substrate specific • membrane-spanning transporter • ATP-hydrolyzing protein
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Siderophores and iron transport
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Group Translocation – Substrates are altered during transportation – Gradient is maintained for the parent solutes, entering the cells by facilitated diffusion – Phosphotransferase system (PTS) • Uses energy from phosphoenolpyruvate (PEP) • Attach a phosphate to specific sugars during transportation glucose glucose-6-phosphate
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Phosphotransferase System (PTS)
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lecture 4 - Symport and Antiport Coupled transportation...

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