Lecture 13 posted - Clonal selection of B cells Secondary...

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BIO 311D LECTURE 13 (Animal) defense systems
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Innate immunity Acquired immunity
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Innate immunity External defenses Physical barriers Mucus production Secretions from skin and mucous membranes Acidity Lysozyme
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Cilia in lungs sweep mucus up to throat
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Internal defenses Phagocytes use phagocytosis to destroy pathogens Macrophages – important phagocytes Innate immunity, cont.
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phagocytosis
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The lymphatic system Only need to know that this system helps to “clean” fluid between cells and returns it to the blood near the heart
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Antimicrobial proteins Cause lysis, help trigger inflammation Interferons are one type Innate immunity, cont.
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Inflammatory response Histamine is primary chemical released Innate immunity, cont. Know these steps
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Natural killer cells Patrol and attack Trigger apoptosis Innate immunity, cont.
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Acquired immunity Lymphocytes - B cells, T cells Antigens Antibodies Epitopes
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Primary immune response
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Unformatted text preview: Clonal selection of B cells Secondary immune response Summary of acquired immune system response Active and Passive Immunization Active immunity which: Develops naturally After immunizations Passive immunity Immediate, short-term protection Conferred naturally or artificially Self, nonself Cells from other individuals Transplanted tissues Blood transfusion Allergies anaphylactic shock Autoimmune responses: Rheumatoid arthritis Lupus Immunodeficiency diseases Inborn or primary immunodeficiency acquired or secondary immunodeficiency Acquired Immunodeficiency Syndrome (AIDS) Compare to: Plant responses to pathogens External physical barrier Recognition of pathogen molecules Hypersensitive response programmed death of infected cells and antibiotic production Systemic acquired resistance...
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Lecture 13 posted - Clonal selection of B cells Secondary...

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