Lecture 5 posted - ® candies: Phenotype Sample 1 Sample 2...

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BIO 311D LECTURE 5 Microevolution( Smallest scale) (population genetics) and the process of natural selection
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Find: Frequencies of the alleles A and a. The genotypic frequencies of AA, Aa and aa.
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***The Hardy-Weinberg equation*** p (f) p q (f) q p 2 homozygous dominant individuals q 2 homozygous recessive individuals 2pq heterozygous individuals
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Conditions which must be met for a population to be in Hardy-Weinberg equilibrium (**************) Random mating No mutations No gene flow (population is isolated) Very large population size (no genetic drift) No natural selection
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So what’s the point of it? (The Hardy-Weinberg theorem)
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Random mating
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Mutation
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Genetic variation changes in a population **Gene flow** - transfer of alleles from one population to the next (increases) **Genetic drift** - chance events cause fluctuations in allele frequencies in a population (decreases) Natural selection
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Genetic Drift
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Unformatted text preview: ® candies: Phenotype Sample 1 Sample 2 Sample 3 Sample 4 Sample 5 Blue 5 1 7 13 Non-blue 48 52 47 53 40 Frequency (blue) 9% 2% 13% 0% 25% Phenotype Sample 1 Sample 2 Sample 3 Sample 4 Sample 5 Blue 45 51 57 43 54 Non-blue 452 448 445 459 450 Frequency (blue) 10% 10% 11% 9% 11% Bigger sample size: The Pounder Genetic drift: special cases 1-Founder effect ( Large Population) 2-Bottleneck effect Examples of bottlenecks Founder effect Natural Selection Fitness Modes of natural selection: Stabilizing selection Directional selection Disruptive selection Balanced polymorphisms Heterozygote advantage 10-20% 5-10% 1-5% Sickle Cell Disease Genotypes Relative fitness Hb-N Hb-N 0.85 Hb-N Hb-S 1.0 Hb-S Hb-S 0.0 Frequency-dependent selection Sexual selection Sexual dimorphism Intrasexual selection Intersexual selection Natural selection is a cause of adaptive evolution...
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This note was uploaded on 01/31/2011 for the course BIOLOGY LE 49610 taught by Professor Hofmannjohann during the Summer '10 term at University of Texas.

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Lecture 5 posted - ® candies: Phenotype Sample 1 Sample 2...

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