chem_237_lecture_1winter2011_and_thermo

chem_237_lecture_1winter2011_and_thermo - Chem 237...

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Introductory Biochemistry Chem 237
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Winter 2011 Introductory Biochemistry Instructor: Dr. Dara Gilbert Office: C2 263 E-mail: d2gilber@uwaterloo.ca Office Hours: MF 1:30-2:30 Tutorial: Thursday 5:30pm-6:20 pm in RCH101. The tutorial will give you a chance to ask questions. Review questions will be discussed. Exams will be given in tutorial
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• Lab starts next week, the week of January 10th
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Chem 237 Course Website: on UW-ACE The website will have course notes, exam answers, announcements, references, etc. Recommended Text: Lehninger Principles of Biochemistry, 5 th edition . Copies will be on reserve in the Davis Centre library Notes: Class Notes will be available on the website in pdf format for you to download before class.
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Chem 237 Exams: Two midterm exams will be given in the tutorial on February 3 rd and March 10th Midterms are not optional this term The final exam will be cumulative and will be given during the final exam period (2.5 hrs). The exam period is April 8 th – 21 st .
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Chem 237 Quizzes: There will be 4 on-line quizzes . The quizzes are graded and the results and answers will be available on-line after everybody has completed the quiz. The quizzes will be on-line every two weeks : They will be posted on Monday and due a week Sunday. The 1 st quiz is posted and due the 16th There will be 2 written assignments as well. They will be due prior to each exam and hopefully help you prepare for the exams. Material in both written and online assignments will be on the exams
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Chem 237 Evaluation: Quizzes 10% These are not optional Assignments 10% 5% each These are not optional Midterm exams 30% 15% each These are not optional Final exam 50% Bonus Participation 0-3 marks added
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Missed exams If you miss one or more of the midterms due to illness, take your Dr.’s note to the science undergrad office and bring me a copy. The weight of the missed exam will be transferred to the final exam. If you miss the final exam you will be given an INC and you make take the exam with the class in the Spring term
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Biochemistry • “Living things are composed of lifeless molecules” (Albert Lehninger) • “Biochemistry is, literally, the study of the chemistry of life”( Voet, Voet and Pratt) • “ Chemistry is the logic of biological phenomena” (Garrett and Grisham)
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Prokaryotes: A single (plasma) membrane no nucleus or organelles Simultaneous transcription and translation Eukaryotes: much larger than prokaryotes Membrane encapsulated nucleus and organelles. Segregated transcription and translation
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cool cell video • multimedia.mcb.harvard.edu
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Chem 237 Introduction Energy : Enthalpy, Entropy and Free energy Role of ATP, coupled reactions
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Chem 237 Water and Buffers Properties of water Action and use of buffers & So s, c
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Chem 237 Amino Acids structure properties role in the cell peptides And, yes, you will need to know the structures of the amino acids and their p K a values!!!
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Chem 237 Protein Structure and Function Protein Purification Protein Folding and disease
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Chem 237 Enzymes: Properties Catalysis Mechanisms Kinetics Regulation
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Chem 237 Nucleic Acids Structures Sequencing The New RNA paradigm
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chem_237_lecture_1winter2011_and_thermo - Chem 237...

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