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Chapter+13 - Fungus:singlecelled, chlorophyll; like...

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  Fungus:  single-celled, colorless plant that lacks  chlorophyll; in humans may be yeast-like or mold- like Superficial skin infections -occur on the surface of  or just below skin or nails Tinea Pedis (athlete’s foot) Tinea Cruris (jock itch) Tinea Corporis (ringworm) Onychomycosis (nail fungus) Candidiasis (yeast infections, thrush) Life-threatening systemic infections -develop inside  the body, such as in the lungs, brain, or GI tract.
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ACTIONS Fungicidal -able to destroy fungi Fungistatic -able to retard the multiplication of fungi USES * Prophylactically to prevent fungal  infection in   immunocompromised patients * Superficial & deep fungal infections * Systemic infections  * Superficial infections of nail beds; oral, anal, &    vaginal areas Review  drugs on pages 117.
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Topical: irritation, burning sensation redness, stinging abdominal pain (vaginal preparations) Systemic: headache rash anorexia, malaise abdominal, joint, or muscle pain N/V, diarrhea
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Antifungals:  use cautiously in patients with  renal dysfunction or hepatic impairment Griseofulvin:  not recommended for people  with severe liver disease Sporanox:  should not be used to treat nail  infections in patients with heart failure Interactions depend on individual drugs.
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Assess pt. for S&S of infection prior to 1 st   dose & document findings Record VS Weigh pt. if receiving amphotericin or  flucytosine due to dosage being determined  by weight Carefully observe pt. every 2-4 hrs. for  adverse reactions when receiving an oral or  parenteral antifungal
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  • Spring '10
  • toole
  • Systemic lupus erythematosus, adverse reactions, fungal infections, infections  *Superficial infections, Immediate adverse reactions

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