BME314quiz1 - B iomaterial nonviable material used in...

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Biomaterial – nonviable material used in medical device, intended to interact with biological systems. Bioactive – materials property that allows them to react with surrounding materials Need for Biomaterials: to replace body part that has lost function, correct abnormalities, assist in healing, improve the function of existing Bulk Properties: *Chemical Properties – bonds (ionic, covalent, metallic, weak) *Mechanical Properties – strength, stress/strain *Electrical Properties - conduction Surface Properties – targeting, interaction w/ environment hydrophilicity and hydrophobicity, smoothness, surface charge Biological Properties –bulk and surface properties Bulk Properties: Chemical Compositions Bonds Microstructure Purity Mechanical Properties Surface properties: Determine tissue interactions Smoothness Surface charge Hydrophilicity/hydrophobicity You’ll find stronger bonds (covalent and ionic) inside ceramics and polymers You’ll find weaker bonds (van der waals and hydrogen) inside metals, polymer chains, and water Biocompatibility – extent of adverse physiological reactions (inflammation, immune response, toxicity) There is no general set of criteria, which if met, qualify a material as being biocompatible. Biodegradability – ability of polymers to break down into smaller units that are either adsorbed by the body or excreted Metals – bone plates, screws Pro – strong, ductile (bonds found as a could so bonds can shift easily) Con – may corrode, difficult to make
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modulus Shear G modulus s Young' or Tensile E shear For , n compressio or Tension For , = = = = γ τ ε σ G E Ceramics – dental, joint replacement Ex. Sapphire, alumina, silica, pyrolytic carbon Pro – biocompatible Con – brittle Polymers – sutures, blood vessels Pro – easy to make Con – can deform with time Composites – combination of two or more materials Pro – strong, tailored Con – difficult to make Polymer advantages over metals and ceramics: Easily designed Non-corrosive in body Can be made biocompatible/degradable Polymer disadvantages: Lower young’s modulus Trace contamination Make sure your ultimate strength and yield strength are close to one another** Area under graph = work to fracture /toughness
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This note was uploaded on 02/01/2011 for the course BME 314 taught by Professor Frey during the Spring '08 term at University of Texas at Austin.

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BME314quiz1 - B iomaterial nonviable material used in...

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