Lecture9_15 - Digestion: Destruction of the primary...

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2/3/11 Main Points Examples of the relationship between protein sequence, structure, and function. Denaturation and digestion of proteins.
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2/3/11
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2/3/11
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2/3/11 Albumin is the most abundant serum protein in blood. It is important in maintaining blood pressure and it is a carrier protein for fatty acids and steroid hormones. What does the function of albumin allow you to predict about the structure of the protein?
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2/3/11
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2/3/11
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2/3/11 No protein Primary Structure Foldin g Shape and position of R-groups Function DNA Sequence Misfoldin g Altered shape No function or altered function Altered primary structure
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2/3/11 Denaturation: Destruction of the secondary and tertiary structure of a macromolecule.
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Unformatted text preview: Digestion: Destruction of the primary structure of a macromolecule. 2/3/11 2/3/11 Denaturati on Sal t He at Acid/Ba se Alcoh ol 2/3/11 2/3/11 Digestio n Enzyme s Hydroly sis Click to edit Master subtitle style 2/3/11 Nucleic Acids 2/3/11 Fig. 5-27ab 5' end 5' C 3' C 5 ' C 3 ' C 3' end (a) Polynucleotide, or nucleic acid (b) Nucleotide Nucleoside Nitrogeno us base 3 ' C 5 ' C Phosph ate group Sugar (pentos e) 2/3/11 2/3/11 Nucleic acids are a polymer of nucleotide monomers 2/3/11 2/3/11 DNA is double stranded 2/3/11 2/3/11 ATP Fig. 8-8 Phosphate groups Ribos e Adeni ne...
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Lecture9_15 - Digestion: Destruction of the primary...

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