Lecture10_6 - Main Points Rate of enzymatic...

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2/3/11 Main Points Rate of enzymatic reactions- inhibitors End-product feedback control What’s the point of cellular respiration? The respiration story- Redox reactions Energy coupled reactions
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2/3/11
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2/3/11 Figure 2-47 Molecular Biology of the Cell (© Garland Science 2008) Catalytic Cycle
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2/3/11 Rate of enzyme controlled rxn Concentration of reactants and products Relative conc. of enzyme and substrate Physical and chemical environment Availability of co-enzyme or co-factor Presence of inhibitor Competitive Non-competitive
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2/3/11 Competitive and Non-Competitive Inhibition Fig. 8-19 (a) Normal binding (c) Noncompetitive inhibition (b) Competitive inhibition Noncompetitive inhibitor Active site Competiti ve inhibitor Substra te Enzy me
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2/3/11 Figure 3-58 Molecular Biology of the Cell (© Garland Science 2008) Figure 3-59 Molecular Biology of the Cell (© Garland Science 2008) Allosteric Regulation
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2/3/11 Examples of inhibition
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2/3/11 End-product negative feedback control A B C D E F G
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2/3/11 End-product negative feedback control A B C D E F G E 1 E 2 E 3 E 4 E 5 E 6
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2/3/11 Example of feedback control Figure 3-57 Molecular Biology of the Cell (© Garland Science 2008)
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Click to edit Master subtitle style 2/3/11 Introduction to Cellular Respiration
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2/3/11 Figure 2-88 Molecular Biology of the Cell (© Garland Science 2008)
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2/3/11 How to sail from Lake Erie to Florida?
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2/3/11 173 m above sea level 74 m above sea level
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2/3/11
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2/3/11
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