Lecture11_3 - Main Ideas Bacterial gene regulation The many...

Info iconThis preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
2/3/11 Main Ideas Bacterial gene regulation The many ways eukaryotic cells regulate gene expression. The relationship between gene regulation and cell specialization.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2/3/11 A Bacterial Operon Figure 7-34 Molecular Biology of the Cell (© Garland Science 2008)
Background image of page 2
2/3/11 Repressible Trp Operon Figure 7-35 Molecular Biology of the Cell (© Garland Science 2008) Low tryptophan in the environment. High tryptophan in the environment.
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2/3/11 Fig. 18-4a (a) Lactose absent, repressor active, operon off DN A Protei n Active represso r RNA polymerase Regulator y gene Promot er Operat or mRN A 5 a 3 a No RNA mad e la c I lacZ
Background image of page 4
2/3/11 Fig. 18-4b (b) Lactose present, repressor inactive, operon on mR NA Prot ein DNA mRNA Inactive repressor Allolacto se (inducer) 5 a 3 a RNA polymera se Permea se Transacetyl ase lac operon a - Galactosidas e la cY lacZ la c A la c I
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Operons that code for proteins needed to synthesize a molecule the bacteria needs (trp) are usually repressible (normally on, turned off when the end-product is readily available). Operons that code for proteins needed to break down a nutrient (lac) are usually inducible (normally off, turned on when the nutrient is The trp and lac operons are examples of negative regulation because they both are turned off by a repressor bound to the operator. Compare and contrast the trp and lac
Background image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 26

Lecture11_3 - Main Ideas Bacterial gene regulation The many...

This preview shows document pages 1 - 7. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online