chap_14-2

chap_14-2 - Chapter 14, Part II Chromosomal rearrangements...

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Unformatted text preview: Chapter 14, Part II Chromosomal rearrangements and changes in chromosome number Chromosomal Rearrangements Deletions Duplications Inversions Translocations Transpositions (i.e. transposable elements) Changes in chromosome number Aneuploidy Monoploidy Polyploidy Transposable elements (TEs) Definition Segment of DNA that can move from place to place within a genome Characteristics 50 10,000 bp long May be present hundreds of times in a genome Can be represented throughout genome 2 types Retroposons Move via an RNA intermediate 3 poly A tail OR Long Terminal Repeats (LTR) Transposons Move directly without an intermediate molecule Origin Retroposons possibly evolved from retroviruses Both retroposons and transposons encode enzymes that move themselves (autonomous ) Poly-A tail at 3 end of RNA-like DNA strand Long terminal repeat (LTRs) oriented in same direction on either end of element Retroposon encodes reverse transcriptase * other than reverse transcriptase, polypeptides Different at end of sequence LTR retroposon transposition...
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This note was uploaded on 02/03/2011 for the course BIOL 2153 taught by Professor Larkin during the Fall '03 term at LSU.

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chap_14-2 - Chapter 14, Part II Chromosomal rearrangements...

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