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BBlecture7S09s - reg1 Regulation of Gene Expression...

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Regulation of Gene Expression Regulation of Gene Expression 9.1: 9.1: Major Modes of Regulation Major Modes of Regulation 5:18: Regulation of Activity of Biosynthetic 5:18: Regulation of Activity of Biosynthetic Enzymes Enzymes 9.2: 9.2: DNA Binding Proteins DNA Binding Proteins 9.3: 9.3: Negative Control of Transcription: Negative Control of Transcription: Repression and Induction Repression and Induction 9.4: 9.4: Positive Control of Transcription Positive Control of Transcription reg1
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metabolic regulation metabolic regulation : : different conditions require different strategies e.g., changes in nutrients available e.g., sporulation regulation permits specific response key cellular enzymes are constitutive yet it is impractical to make every protein all the time excess proteins may be costly some proteins may be made only when needed → cellular activities can be regulated at multiple levels reg2
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possible mechanisms of regulation: possible mechanisms of regulation: control of expression expression control of activity activity (Fig 9.1, 12 th ed) reg3
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