Control Survival Data1

Control Survival Data1 - Male Rat control data died on...

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Unformatted text preview: Male Rat control data died on study prior to terminal sacrifice (completes) Total Day Chemical V2O5 Day 372 467 502 561 589 610 612 617 619 624 628 636 638 650 652 666 669 677 694 701 705 708 710 Decalin Day Tumors 421 561 572 581 589 614 628 638 658 666 678 688 694 700 706 728 Naphthalene Day 473 516 572 615 624 634 639 657 658 660 673 678 692 695 703 708 709 713 721 726 Completes 372 1 408 1 421 1 467 1 467 1 473 1 476 1 492 1 495 1 502 1 505 1 516 1 525 1 537 1 552 1 554 1 561 3 569 1 572 2 581 1 589 5 592 1 600 1 610 1 612 1 614 1 615 2 617 2 619 1 624 4 628 2 629 1 634 1 636 1 638 3 639 2 647 1 649 1 650 1 652 1 656 1 657 1 658 2 660 1 666 5 669 1 671 1 672 2 673 1 Tumors 1 1 1 1 3 1 1 1 1 1 1 1 1 1 1 4 1 1 1 1 1 1 1 1 2 1 1 1 1 1 2 1 1 2 1 2 1 1 1 677 678 679 687 688 692 694 695 697 700 701 703 705 706 708 709 710 713 714 721 723 726 728 N 1 3 2 2 1 1 3 1 1 2 4 2 1 1 2 2 1 2 1 1 1 1 1 108 Naphthalene Tumors 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 MeiBu Ketone Day Tumors 467 492 505 554 589 592 624 629 671 679 687 701 713 723 InP Day 1 1 1 1 1 1 1 1 1 2 2 3 1 1 408 476 495 525 537 552 569 600 617 624 639 647 649 656 672 697 700 703 709 714 Tumors 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 Control Survival Data Female Mice B6C3F1 Inhalation studies Battelle NW Study Vanadium Pentoxide TR-507 Decalin TR-513 Week Tumor No Tumor Total Tumor No Tumor Total 20 21 22 23 24 25 26 1 1 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 1 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 Naphthalene TR-500 Tumor 1 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 Sum1 Sum2 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 21 17 1 2 1 1 1 2 1 1 1 1 38 25 9 21 2 17 11 38 5 25 12 7 12 1 1 1 1 1 1 2 1 2 1 37 12 37 Naphthalene TR-500 No Tumor Total 20 21 22 23 24 25 26 27 28 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 Indium Phosphide TR-499 Tumor No Tumor Total Methyl iBu Ketone Tumor No Tumor Total 1 1 1 1 1 1 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 25 1 1 1 1 1 1 35 1 1 27 5 27 15 3 15 1 1 10 42 8 42 7 25 6 10 13 35 Propylene glycol mono t-Butyl ether Tumor No Tumor Total 20 21 22 23 24 25 26 27 28 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 Stoddard Solvent Tumor No Tumor Total 8.Divinylbenzene Tumor 1 1 1 1 1 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 24 15 1 1 2 2 1 1 1 39 1 1 23 1 13 1 1 1 1 1 1 1 1 1 1 36 1 1 1 2 20 6 24 5 15 11 39 8 23 6 13 14 36 12 20 8.Divinylbenzene No Tumor Total 20 21 22 23 24 25 26 27 28 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 9.Gallium Arsenide Tumor No Tumor Total 10.Glutaraldehyde Tumor No Tumor Total 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 2 14 34 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 3 1 1 2 1 1 1 3 1 1 1 1 2 24 10 26 1 1 1 2 36 12 38 12 2 12 32 10 32 3 5 3 35 15 35 4 14 16 34 Control Survival Data Male Rats F344 Inhalation studies Battelle NW Study 1.Vanadium Pentoxide TR-507 2.Decalin TR-513 Week Tumor No Tumor Total Tumor No Tumor Total 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 1 54 55 1 56 57 58 59 60 1 61 62 63 64 65 66 67 68 1 1 69 3.Naphthalene TR-500 Tumor 1 1 1 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 Sum 1 Smu 2 1 1 1 1 1 1 2 1 1 1 1 2 2 1 1 1 3 2 2 1 1 2 2 4 1 1 1 1 3 20 3 2 2 1 1 2 2 4 1 1 1 1 3 20 1 1 2 1 1 2 2 1 1 1 1 1 2 1 2 1 1 29 1 1 2 1 2 1 1 29 3 2 2 1 1 1 1 24 27 20 0 0 28 20 19 29 2 0 21 29 20 24 3.Naphthalene TR-500 No Tumor Total 1 1 Study Week 4.Indium Phosphide TR-499 Tumor No Tumor Total 20 21 22 23 24 25 26 27 28 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 1 59 60 61 62 63 64 65 2 66 1 67 68 1 69 5.Methyl iButyl Ketone Tumor No Tumor Total 1 1 1 1 1 1 1 2 1 1 1 1 4 2 2 1 1 1 1 25 1 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 2 1 1 24 2 21 26 1 1 1 1 1 2 1 2 1 2 1 1 25 2 22 27 1 2 3 1 1 32 1 2 3 1 1 32 1 2 1 2 3 1 23 25 1 1 17 32 0 0 17 32 6.Propylene glycol mono t-Butyl ether Tumor No Tumor Total 20 21 22 23 24 25 26 27 28 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 7.Stoddard Solvent Tumor No Tumor Total 8.Divinylbenzene Tumor 1 1 1 1 1 1 1 1 1 1 1 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 1 1 1 1 1 1 ` 1 1 2 1 1 2 1 3 2 1 1 1 1 1 1 1 2 1 3 3 1 1 1 3 2 1 28 1 1 1 2 2 2 1 1 1 5 1 2 1 5 1 2 3 2 1 28 1 1 2 31 1 2 1 2 2 27 2 2 27 20 27 3 0 23 27 15 28 6 0 21 28 19 31 8.Divinylbenzene No Tumor Total 20 21 22 23 24 25 26 27 28 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 9.Gallium Arsenide Tumor No Tumor Total 10.Glutaraldehyde Tumor No Tumor Total 1 1 1 1 1 1 1 1 1 1 1 2 2 1 1 1 2 1 1 1 2 31 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 1 1 2 1 1 2 1 1 2 2 2 2 2 1 1 2 1 1 4 1 1 1 1 2 1 3 1 2 1 2 1 1 1 4 3 1 1 2 1 2 1 3 1 2 1 2 1 1 3 2 1 2 3 1 1 1 2 2 1 2 12 1 3 2 1 3 3 1 1 2 2 2 2 2 12 3 1 1 1 1 14 0 1 1 14 0 0 19 31 30 14 1 0 31 14 34 12 3 0 37 12 Control Survival Data Female Rats F344 Inhalation studies Battelle NW Study Vanadium Pentoxide TR-507 Decalin TR-513 Week Tumor No Tumor Total Tumor No Tumor Total 20 21 22 23 24 25 26 27 28 29 30 31 32 33 1 1 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 1 52 53 54 55 56 57 58 59 60 61 62 63 64 65 1 1 66 1 1 67 68 69 Naphthalene TR-500 Tumor 1 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 Sum 1 Sum 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 2 3 1 1 2 2 2 1 1 1 1 1 2 30 1 1 1 2 33 1 2 1 28 17 30 0 3 17 33 13 28 4 4 4 1 1 1 2 1 3 1 1 1 2 1 32 17 32 3 3 1 2 2 24 15 26 1 1 3 Naphthalene TR-500 No Tumor Total 20 21 22 23 24 25 26 27 28 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 Indium Phosphide TR-499 Tumor No Tumor Total Methyl iBu Ketone Tumor No Tumor Total 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 2 3 3 1 1 2 2 28 18 30 1 4 3 4 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 1 1 1 1 2 1 1 2 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 2 1 3 1 1 1 1 1 1 1 1 2 2 1 1 2 2 15 35 1 30 10 31 4 4 4 1 34 14 35 20 14 20 1 15 15 35 Propylene glycol mono t-Butyl ether Tumor No Tumor Total 20 21 22 23 24 25 26 27 28 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 Stoddard Solvent Tumor No Tumor Total 8.Divinylbenzene Tumor 1 1 1 1 1 1 1 1 1 1 1 1 1 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 1 1 1 1 1 1 1 1 1 1 1 2 2 1 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 32 1 2 1 1 1 1 33 1 2 1 27 1 1 1 1 1 2 1 2 1 37 1 9 1 1 1 1 1 1 30 11 32 6 1 17 33 13 27 1 9 14 37 15 30 8.Divinylbenzene No Tumor Total 20 21 22 23 24 25 26 27 28 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 9.Gallium Arsenide Tumor No Tumor Total 10.Glutaraldehyde Tumor No Tumor Total 1 1 1 1 2 3 1 1 1 1 1 1 1 1 3 1 1 1 1 1 1 33 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 1 1 1 1 1 1 1 1 1 1 1 1 1 1 3 1 2 3 1 1 2 2 3 1 1 2 3 1 1 1 1 3 3 3 3 2 21 1 1 3 3 3 3 2 21 1 1 1 1 3 1 2 1 1 1 25 1 1 1 1 1 3 1 2 1 1 1 26 1 2 3 17 33 27 21 2 0 29 21 22 25 1 1 23 26 Control Survival Data Male Mice B6C3F1 Inhalation studies Battelle NW Study Vanadium Pentoxide TR-507 Decalin TR-513 Week Tumor No Tumor Total Tumor No Tumor Total 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 1 56 57 58 59 60 1 61 62 63 64 65 66 67 68 1 69 Naphthalene TR-500 Tumor 1 1 1 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 Sum1 Sum2 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 2 1 30 1 9 1 2 1 1 39 34 9 30 2 9 11 39 8 34 6 2 6 1 1 1 1 1 1 1 1 40 10 40 Naphthalene TR-500 No Tumor Total 20 21 22 23 24 25 26 27 28 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 Indium Phosphide TR-499 Tumor No Tumor Total Methyl iBu Ketone Tumor No Tumor Total 1 1 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 1 1 2 1 1 1 1 1 1 1 2 2 1 2 2 2 2 1 1 2 2 2 1 2 1 2 1 1 1 30 9 31 7 3 7 1 1 37 12 38 35 5 1 40 10 35 0 5 10 40 Propylene glycol mono t-Butyl ether Tumor No Tumor Total 20 21 22 23 24 25 26 27 28 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 Stoddard Solvent Tumor No Tumor Total 8.Divinylbenzene Tumor 1 1 1 1 1 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 2 1 18 1 1 1 1 1 1 1 3 1 1 2 1 35 1 1 1 2 1 1 1 2 1 1 1 2 1 1 1 1 1 1 1 1 1 27 7 1 34 31 17 13 18 2 17 15 35 14 27 2 7 16 34 8 31 8.Divinylbenzene No Tumor Total 20 21 22 23 24 25 26 27 28 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 9.Gallium Arsenide Tumor No Tumor Total 10.Glutaraldehyde Tumor No Tumor Total 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 10 41 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 1 1 2 1 1 2 2 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 1 25 10 1 2 2 1 35 2 2 1 1 2 1 23 9 1 9 2 2 1 1 2 1 32 19 32 1 10 9 41 13 25 1 10 14 35 18 23 ...
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