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Unformatted text preview: like blood, will get more; ethanol is soluble in fat, and women tend to have higher % of fat. Liver is primary location for metabolism. Liver uses CYP2E1. Rate of metabolism is set at an amount per unit of time, and varies with age, and tolerance. Steps in metabolism: Alcohol ALCOHOL DEHYDROGENASE (ADH) Acetaldehyde ACETALDEHYDE DEHYDROGENASE (ALDH) (ANTABUSE, DISULFIRAM) Acetic acid OXIDIZED CO2 (lungs) + H2O (urine) + energy Excretion occurs mainly in the liver and lungs (non-metabolized)....
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- Spring '11