addiction Benzo

addiction Benzo - chronic anxiety, alcohol detox, muscle...

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Benzodiazepines Librium- first one in 1960 Valium- 1963- long lasting due to active metabolites; tolerance and withdrawal occurs Cross-tolerance and cross-dependence with other depressants; this allows for their use in withdrawal of alcohol. Act by inhancing neural inhibition by the GABA system(GABA is inhibitory already)
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BZ Varying half-life 1-75 hours; very safe This results in different preferences for use: surgery, insomnia, acute anxiety,
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Unformatted text preview: chronic anxiety, alcohol detox, muscle spasms, seizures BZs potentiate each other and other depressants resulting in overdose BZ Effects include drowsiness, suppress REM, change EEG patterns during other sleep stages; anterograde amnesia Rebound effects- need to be distinguished from the symptoms for which drug was started; Buspar-serotonin; no withdrawal; not abused; for long-term, takes a month or so to kick in....
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This note was uploaded on 02/05/2011 for the course PSY 477 taught by Professor Ceasar during the Spring '11 term at CSU Long Beach.

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addiction Benzo - chronic anxiety, alcohol detox, muscle...

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