addiction opioids - mu in locations • Being in the...

Info icon This preview shows pages 1–5. Sign up to view the full content.

View Full Document Right Arrow Icon
Opiates/Opioids Multiple opioid receptors Multiple opioid receptor sites-brain, brain stem, spinal cord, digestive system, many organs While similar to endogenous opioids, opioid/opiate drugs cause more intense reactions Each drug has its unique affinity for receptor sites
Image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Opioid Receptors Three main opioid receptors called mu, kappa, delta; probably metabotropic Mu is widely distributed in brain and spinal cord areas resulting in analgesia, positive reinforcement, cardiovascular and respiratory depression, cough control, nausea, vomiting (brain stem)
Image of page 2
DeltaReceptors Delta receptors are more restricted than
Image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 4
Image of page 5
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: mu in locations • Being in the neocortex, substantia nigra, nucleus accumbens, and olfactory areas, what results would you expect? Kappa Receptors • Distinct and limited distribution • Found in sub-cortex areas that regulate bodily functions like water balance, temperature control, neuroendocrine function • Hormonal systems impacted resulting in male decrease in testosterone and delayed periods in women Side effects • Slurred speech • Poor coordination • Pinpoint pupils* • Suppressed cough (for whom might this be a disadvantage?) • Constipation* • *Little tolerance develops...
View Full Document

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern