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lecture 20 emotion_stress

lecture 20 emotion_stress - Lecture 20 Emotion and Stress...

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12/8/2008 1 Lecture 20: Emotion and Stress Overview Review Caffeine What is an Emotion Theories of Emotion Limbic system Stress St Stress response Chronic effects % Basic pharmacology % normally consumed orally through beverages in Caffeine which it is present % completely absorbed from GI tract 30 60 minutes % average half life ~4 hrs (but varies from person to person) %
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12/8/2008 2 % high doses experience feelings of tension and anxiety % Individuals suffering from panic disorders are hypersensitive to caffeine Behavioral effects % Subjective effects (low to moderate doses) % feelings of well being % enhanced energy or vigor % increased alertness and ability to concentrate % self confidence, increased work motivation, enhanced sociability Physiological effects % increased blood pressure and respiration rate % enhanced water excretion (diuresis) % stimulation of catecholamines, particularly NE % chronic caffeine use may increase risk for heart disease or stroke % mildly effective in treatment of nonmigraine headache
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12/8/2008 3 Tolerance and dependence % chronic use leads to tolerance to subjective, and physiological effects % dependence: individuals experience lethargy or fatigue when skipping first cup of coffee Mechanisms of caffeine action % does not directly influence catecholamine systems (as other stimulants) % blockade of GABA A receptors % blockade of adenosine (A 1 , A 2A ) receptors Tobacco % Nicotine – major psychoactive ingredient % 4,000 other chemicals in tobacco % 3 000 000 d th ld id i t d ith t b 3,000,000 deaths worldwide are associated with tobacco % About 70% of those who experiment with smoking become addicted (highest of all drugs of abuse) % Only about 20% of attempts to stop are successful
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