311C F10 Objectives Ch 6&7

311C F10 Objectives Ch 6&7 - Objectives for...

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1. Describe the structure of the nuclear envelope of the eukaryotic cell, including membranes and pores. The nuclear envelope encloses the nucleus separating it from the cytoplasm. It has a double membrane and each consists of a lipid bilayer. Pores regulate the entry and exit of molecules from the nucleus. 2. What are ribosomes made of, and what is their function? When is a ribosome "bound" vs "free"? Ribosomes are particles made of ribosomal RNA and protein. They carry out protein synthesis in the cytosol and on the outside of the endoplasmic reticulum or the nuclear envelope 3. How do smooth ER and rough ER differ in appearance (structure) and in function? Smooth ER – no ribosomes and synthesizes lipids, metabolizes carbohydrates, detoxifies poison, and stores calcium Rough ER – has ribosomes that secrete glycoproteins, distribute transport vesicles, and is the membrane factory for the cell 4. Name two organelles considered part of the endo-membrane system and two organelles that are not in the endo-membrane sytem. 2 organelles in the endo- membrane system is the endoplasmic reticulum and golgi apparatus, 2 organelles that are not in the endomembrane system are nitochondria and chloroplasts. 5. Describe how transport vesicles integrate the endo-membrane system. (Concept check 6.4) The transport vesicles connect all of the endomembrane system together. 6. Describe how ribosomes, rough ER, Golgi and transport vesicles are involved together in the synthesis, chemical modification, trafficking, and export of a protein hormone. Ribosomes secrete glycoproteins, the rough ER distributes transport vesicles, the golgi apparatus sorts and packages materials into transport vesicles. 7. How could you use cell fractionation and centrifugation in order to study the distribution of radioactively labeled molecules inside different types of organelles? Cell fractionation: Separates cellular components based on size and density 8. Which organelles are involved in the synthesis (condensation) of triglycerides (fats and oils)? The smooth ER 9. Which type of organelle is involved in the digestion (hydrolysis) of triglycerides (fats and oils)? Lysosomes
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10. Tell the ‘life story’ of a membrane protein (e.g., ‘birth, maturation, placement,
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311C F10 Objectives Ch 6&7 - Objectives for...

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