Exam3A - Biology of Cancer and AIDS Exam 3A_Key Instructor:...

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Cancer and AIDS Exam 3A Page 1 Biology of Cancer and AIDS Exam 3A_Key Instructor: Wilmore Webley, Ph.D. Instructions: The correct answer is highlighted in red font 1. HIV infection can induce Syncytium formation; this aspect of viral pathology takes place ____________. (A) only in uninfected circulating T-lymphocytes (B) when Gp120 on infected cells bind CD4 on the surface of uninfected cells (C) only in individuals infected with HIV-2 (D) when HIV particles cling together forming a large mass of over 50 viral particles 2 . Which of the following is a true statement about the relationship between alcohol and HIV? (A) Alcohol has no real impact on HIV transmission risk (B) HIV can be transmitted by patrons sharing alcoholic beverages (C) Alcohol causes epithelial tissue damage increasing the likelihood of viral entry (D) Alcohol increases high-risk sexual behaviors and injection drug use, both HIV transmission routes 3 . Which of the following is the most commonly used laboratory test to detect HIV? (A) ELISPOT (B) ELISA (C) PCR (D) DNA 4 . Which of the following statements concerning the relationship between HIV-1 and HIV-2 is true? (A) The modes of transmission for HIV-1 and -2 are very different (B) Immunodeficiency progresses more slowly in HIV-2 patients (C) HIV-2 causes a more serious infection than HIV-1 (D) HIV-1 is found predominantly in West African countries 5 . In the initial events of HIV infection the _______ molecule on the surface of the virus binds to the _______ receptor present on susceptible cells. (A) CD4, p24 (B) Gp120, CD4 (C) CD4, Gp17 (D) Gp41, CD4 6. Based on our conversation in class on the origins of HIV, when did HIV first cross the species barrier, evolving from a simian virus to a human virus? (A) The 1700s (B) The 1930s (C) The 1950s (D) The 1970s (E) The 1980s 7 . In 1993 the CDC revised the classification system for HIV infection to primarily emphasize the clinical importance of ___________. (A) the 10 year asymptomatic period (B) PCP as an opportunistic infection in AIDS (C) HIV viral load in the peripheral blood (D) CD4 cell count in the categorization of HIV conditions
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Cancer and AIDS Exam 3A Page 2 8 . Which of the following is the most likely outcome if a technician who performs HIV tests forgot to perform the wash step after adding the enzyme conjugated second antibody? (A) Lucky for her, omitting the last wash step has no effect on the test (B) All test wells, including HIV negative ones will appear positive (C) All test wells will appear negative (D) Half of the wells will appear positive and the other half negative (E) All wells will be indeterminate 9 . HIV is NOT typically present in _________. (A) sweat
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This note was uploaded on 02/06/2011 for the course MICROBIO 160 taught by Professor Hamilton during the Spring '08 term at UMass (Amherst).

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Exam3A - Biology of Cancer and AIDS Exam 3A_Key Instructor:...

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