FinalB - Biology of Cancer and AIDS Final Exam B Key...

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Final Exam v.B Page 1 Biology of Cancer and AIDS Final Exam B Key Instructor: Wilmore Webley, Ph.D. Instructions: Correct answers are in red font 1. In "Let me answer your question #3" you answered questions from a NYT series on a drug called PLX4032 to treat melanoma. This drug is designed to ______. (A) prevent P53 gene function in all skin cells (B) halt the replication of basal cells in the skin (C) prevent chromosome separation in cancer cells (D) bind to the B-RAF protein found in 50% of melanomas (E) act like a protease degrading all cancerous proteins 2. Mutated proto-oncogenes play important roles in cancer development. What is the normal role of these genes in a noncancerous cell? (A) Repair damaged DNA (B) Promote cell growth under the proper conditions (C) Stimulate the immune system to fight cancer (D) Halt cell cycle at checkpoints 3. Massive HIV/AIDS public awareness and condom distribution campaigns can significantly reduce the spread of the disease. Which country is a good example of this strategy? (A) China (B) South Africa (C) Lithuania (D) Botswana (E) Thailand 4. Certain gene mutations are higher risk factors for cancer than others. Which of the following tumor suppressor gene mutations is involved in most cancers? (A) BRCA1 and 2 genes (B) Rb gene (C) p53 gene (D) Ras gene (E) APC 5. Although African Americans represent only _____ of the US population, they account for ______ of all AIDS cases at the end of 2008. (A) 2%, 61% (B) 30%, 66% (C) 12%, 45% (D) 15%, 75% 6. Susan has been smoking for 12 years and was recently diagnosed with the most aggressive type of lung cancer. Which of the following types of lung cancer does she have? (A) Adenocarcinoma (B) Squamous cell carcinoma (C) Small cell carcinoma (D) Large cell carcinoma 7. An individual who smokes cigarettes and also drinks alcohol is at a significantly increased risk of oropharyngeal cancer. Which of the following correctly describes the relationship between alcohol and smoke that leads to this higher rate of cancer? (A) Alcohol causes mutation, cigarette smoke causes mutated cells to proliferate (B) Smoke causes mutations; alcohol causes mutated cells to grow (C) Alcohol is converted by smoke into a carcinogen (D) Alcohol prevents smoke from being inactivated by the immune system
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Final Exam v.B Page 2 8. The transmission of HIV can be limited by all of the following methods except_____________. (A) using a condom during sexual encounters (B) disinfecting needles used to inject drugs (C) limiting number of sexual partners (D) using mosquito repellent 9. Which of the following classes of HIV drugs prevent HIV replication by inserting faulty DNA building blocks as the new DNA strand is made by reverse transcriptase? (A) Nucleoside reverse transcriptase
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FinalB - Biology of Cancer and AIDS Final Exam B Key...

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