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Unformatted text preview: A research group is studying imprinted genes, due to their implication in a variety of human disorders such as Prader-Willi syndrome, Beckwith-Wiedemann syndrome, bipolar disorder and various types of malignant tumors. The gene above is called Impact and its found on Chromosome 8 in mice and a human homolog exists on Chromosome 18. Mating crosses in this Fgure are female x male, and represent reciprocal cross using C57 B6 mice and J¡1 mice. (cDNA = complementary DNA, meaning RNA that has been back transcribed into DNA and measured) E1. Which of the following is accurate? a. This gene is biallelically expressed, equal expression from both alleles b. This gene is biallelically expressed, but with more maternal expression than paternal c. This gene is biallelically expressed, but with more paternal expression then maternal d. This gene is monoallelically expressed, only from the maternal allele e. This gene is monoallelically expressed only from the paternal allele If loss of the protein this gene produces results in a developmental disorder, which of the following is...
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This document was uploaded on 02/06/2011.
- Spring '09