CHAPTER 14 - Bioaccumulation: Toxicants can accumulate and...

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CHAPTER 14: ENVIRONMENTAL HEALTH AND TOXICOLOGY Central case: alligators and endocrine disruptors at Lake Apopka, FL Environmental health threats: o Physical o Biological o Chemical o Cultural Endocrine disruptors: mimic hormones Radon (odorless gas), lead, asbestos (bad to inhale) Toxicity: degree of ham toxicant can cause TOXICANTS Carcinogens: chem./radiation that causes cancer Mutagens: mutation in DNA – doesn’t necessarily cause cancer Teratogens: affect development of embryo—birth defects Neurotoxin: affect nervous system Endocrine disruptor: affect hormones (thru bloodstream) o Sometimes brain and nervous system too Bisphenol-A in plastic A lot of toxicants thru water Pesticide drift – airborne
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Unformatted text preview: Bioaccumulation: Toxicants can accumulate and move up food chain Biomagnification: more toxicants up the food chain (DDT) Ames test: bacterial assay for mutagens, easy screening of suspected toxins LD50: 50% of individuals killed from dose o High LD50 = low toxicity o Low LD50 = high toxicity ED50: dose affect 50% individuals Threshold dose: response occur after certain dose Acute exposure: higher exposure over short time Chronic exposure: lower exposure over long time Synergistic effects: more than or different than sum of effects Innocent until proven guilty approach Precautionary principle approach...
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This note was uploaded on 02/09/2011 for the course ENVSCI 101 taught by Professor Don'tremember during the Spring '11 term at Rutgers.

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