Study Guide 2 & 3 - BCMB3100 Problems: Chapter 3...

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Handout 2 BCMB3100 Chapters 3-4 Problems: Chapter 3 (4,6,8,9,10,15) Chapter 2 1) Given pKa’s, be able to plot the titration (H.-H.) curve for a polyprotic acid and identify on the curve the dominant form of the acid. 2) Know how carbonate buffers blood. Identify carbonic acid, bicarbonate and carbonate. IF CO2 LEAVES, pH goes up. Hyperventillation increases Blood pH by removing CO2. 3) During diabetic ketoacidosis the pH of the blood decreases. How does the body respond and why? 4) How does the dangerous ‘paper bag rebreathing’ technique affect blood pH? How does a bicarbonate drip affect blood pH? Chapter 3 5) Know names (full, one and three letter) of all 20 natural occurring amino acids. Know ‘pK a rule of thumb’ for the α -amino (~9) and carboxylate groups (~3) of the amino acid backbone. 6) Know the titration curve (Henerson-Hasselbalch) for zwitterions. Be able to identify regions of the curve that are dominated by positive, negative or neutral ions. Be able to identify the pI on the curve. 7) Know the difference between L and D isomers of amino acids, and which form is found in proteins.
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This note was uploaded on 02/07/2011 for the course BCMD 3100 taught by Professor Rose during the Spring '11 term at University of Georgia Athens.

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