s17 - Transport of O Transport of O 2 2 and CO and CO 2 2...

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Unformatted text preview: Transport of O Transport of O 2 2 and CO and CO 2 2 How does O 2 get to the cells that need it and CO 2 get back to the gas exchangers? Ecological Correlates: The P 50 ~ 1/affinity Normoxic vs. Hypoxic environments http://en.wikipedia.org/wiki/File:HbA_vs_HbF_saturation_curve.png Transport of O Transport of O 2 2 and CO and CO 2 2 How does O 2 get to the cells that need it and CO 2 get back to the gas exchangers? Ecological Correlates: The P 50 ~ 1/affinity Normoxic vs. Hypoxic environments Fetal vs. Maternal Hb http://en.wikipedia.org/wiki/File:HbA_vs_HbF_saturation_curve.png Transport of O Transport of O 2 2 and CO and CO 2 2 How does O 2 get to the cells that need it and CO 2 get back to the gas exchangers? Ecological Correlates: The P 50 ~ 1/affinity Normoxic vs. Hypoxic environments Fetal vs. Maternal Hb http://en.wikipedia.org/wiki/File:HbA_vs_HbF_saturation_curve.png Which Hb has the lower P 50 ? Transport of O Transport of O 2 2 and CO and CO 2 2 How does O 2 get to the cells that need it and CO 2 get back to the gas exchangers? Ecological Correlates: The P 50 ~ 1/affinity Normoxic vs. Hypoxic environments Fetal vs. Maternal Hb http://en.wikipedia.org/wiki/File:HbA_vs_HbF_saturation_curve.png Fetal Hb has a lower P 50 than maternal Hb So, at any given blood P 02 , there is more free oxygen in the maternal blood stream diffuses across the plancenta Transport of O Transport of O 2 2 and CO and CO 2 2 How does O 2 get to the cells that need it and CO 2 get back to the gas exchangers? Ecological Correlates: The P 50 ~ 1/affinity Normoxic vs. Hypoxic environments Fetal vs. Maternal Hb Why is Hb DC sigmoidal? Transport of O Transport of O 2 2 and CO and CO 2 2 How does O 2 get to the cells that need it and CO 2 get back to the gas exchangers? Ecological Correlates: The P 50 ~ 1/affinity Normoxic vs. Hypoxic environments Fetal vs. Maternal Hb Why is Hb DC sigmoidal? Hb-Hb interactions Transport of O Transport of O 2 2 and CO and CO 2 2 How does O 2 get to the cells that need it and CO 2 get back to the gas exchangers?...
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s17 - Transport of O Transport of O 2 2 and CO and CO 2 2...

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