BZ350S10Exam3

BZ350S10Exam3 - BZ350 Molecular and General Genetics THIRD...

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1 BZ350 Molecular and General Genetics THIRD EXAM (April 16, 2010) NAME ____________________________ I.D. No: __________________________ SECTION A: Multiple choice questions (Total points 10): Circle the most appropriate answer for each question. 1. Which of the following is not true of RNA? A. It is acidic B. It contains dexoyribose sugar C. It contains uracil D. It mostly exists in double stranded from E. B and D 2. A nucleotide consists of A. a pentose sugar and a nitrogenous base B. a pentose sugar, a nitrogenous base and a phosphate C. a pentose sugar and a phosphate D. a nitrogenous base and a phosphate E none of the above 3. In eukaryotes mRNA, tRNA and rRNA are synthesized by ____, ____ and ___ respectively, A) RNA polymerase I, RNA polymerase III, RNA polymerase II B) RNA polymerase I, RNA polymerase II, RNA polymerase III C) RNA polymerase II, RNA polymerase III, RNA polymerase I, D) RNA polymerase II, RNA polymerase I, RNA polymerase III, E) RNA polymerase III, RNA polymerase I, RNA polymerase II, 4. If 28% of the bases in a mouse chromosome are cytosine what is the percentage adenine in this chromosome? A) 56% B) 22% C) 48% D) 72% E) 28% 5. The group of enzymes that are able to relax (unwind) supercoils in DNA is called: A) primases B) helicases C) topoisomerases D) telomeres E) ligases 6. What property of the genetic code allows the use of several codons for a particular amino acid? A) accuracy of transmission B) near universality C) degeneracy D) non-overlapping codons E) reading frame
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2 NAME ____________________________ I.D. No: __________________________ 7. Experimental evidence in support of semiconservative mode of replication came from A) Griffith’s Experiment B) Avery, McLeod and McCarty Experiment C) Messelson-Stahl Experiment D) Chargaff’s experiment E) Jacob and Monad Experiment 8. Synthetic mRNAs that were used to investigate the nature of the genetic code were synthesized with the enzyme A. RNA polymerase. B. DNA polymerase. C. polynucleotide phosphorylase. D. reverse transcriptase. E. RNA ligase. 9. Which of the following is the accurate representation of nucleotide chains, where S = sugar, P = phosphate, and B = nitrogen base (A, G, C, T, or U)? A) B) C) D) 10. Frameshift mutation is caused by A. addition of a base B. deletion of a base C. substitution of a base D. A & B E. A, B & C SECTION B: Fill-in questions. Fill in the blank with a word or a phrase that best completes the sentence. ( 20 points) 11. 5’ to 3’ Nucleic acids (DNA and RNA) are synthesized in _________ direction. 12. ___Sigma factor________ Promoter recognition in prokaryotic genes requires ____ factor. 13. 64; 61, three termination
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BZ350S10Exam3 - BZ350 Molecular and General Genetics THIRD...

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