NucAcidStrFunct_Student

NucAcidStrFunct_Student - Nucleic Acids: Structure and...

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Click to edit Master subtitle style 2/10/11 Nucleic Acids: Structure and Function
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2/10/11 Learning Objectives Understand the basic structure of nucleotides Describe the various structures adopted by DNA and RNA Articulate the important differences between RNA and DNA structures that give them their distinct functions
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2/10/11 Central Dogma DN A Protei n RN A
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2/10/11 DNA and RNA Structure Protein is a polymer of amino acids DNA and RNA are polymers of nucleotides
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2/10/11 Picture 3 Nucleotide structure and nomenclature
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2/10/11 Nucleotide structure and nomenclature Picture 5 Phosphodiester bond connects nucleotides in DNA and RNA polymers
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2/10/11 DNA Structure
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2/10/11 Figure 1.10a: Segment of a polydeoxyribonucleotide: Extended structure DN A By convention DNA and RNA Sequences are written 5’ … 3’ L q R Sugar phosphate backbone Bas es Phosphodiester bond
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DNAs vary greatly in size
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2/10/11 DNA does not usually exist as an extended single strand. Double stranded in cells
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2/10/11 Figure 4-4 Molecular Biology of the Cell (© Garland Science 2008) Double strands are stabilized by hydrogen bonds between complimentary bases on anti-parallel strands. (complimentary base pairing)
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2/10/11 Complimentary base pairing Chargaff’s rule A pairs with T (U in RNA) G pairs with C Exotic base pairing rules (triplex DNA)
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NucAcidStrFunct_Student - Nucleic Acids: Structure and...

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