MIBO journal Article presentation

MIBO journal Article presentation - Telithromycin and

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Click to edit Master subtitle style Telithromycin and Quinupristin-Dalfopristin Jamie Checkley Jessica Hall
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Click to edit Master subtitle style Background Information
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Purpose of Experiment Evaluate the current antimicrobial resistance of Streptococcus pyogenes in Taiwan using the SMART program, especially against macrolides.
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Significance of the Experiment Better understanding of the organisms and their resistance to the drugs could aid in the development of new drugs or inhibition of further resistance.
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Streptococcus pyogenes Most common skin and soft tissue disease Can causes life threatening invasive disease
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Streptococcus pyogenes Susceptible to Penicillin Resistant to macrolides Resistance varies by country
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Telithromycin First ketolide antibiotic to enter clinical use Used to treat respiratory infections. Sold under the brand name of Ketek
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Telithromycin Mechanism of action: prevents bacteria from growing by interfering with protein synthesis Active against S. pyrogenes isolates with ermAM(B), mefA mediated resistance
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Click to edit Master subtitle style Methodologies and Experimentation
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Collecting the Sample 419 isolates of S. pyogenes were collected from patients at nine hospitals across Taiwan from January 2000 to December 2001
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TABLE 1: Sources of 419 isolates of S. pyogenes
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This note was uploaded on 02/08/2011 for the course MIBO 3510L taught by Professor Dustman during the Fall '08 term at University of Georgia Athens.

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MIBO journal Article presentation - Telithromycin and

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