L15 - Monday,November1,2010 Reading Chapter11,pages363375...

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Monday, November 1, 2010 Membranes and Permeability Reading: Chapter 11, pages 363-375  Objectives: General strategies cells use to work within the rules of chemistry:  o enzyme catalysis o coupled reactions o compartmentation Thinking about cells and compartmentation in physical terms.  o Barbara McClintock: "a feeling for the organism". o A eukaryotic cell resembles a house, with each compartment being a  different room. o The boundaries of each compartment (the walls of the house) are  biological membranes. Properties of biological membranes.  o Impermeant to ions and other polar molecules, including protons. o Composed of phospholipids. Phospholipids are  amphipathic , with a polar head group and  hydrophobic hydrocarbon tails. Phospholipids pack to form  bilayers  consisting of two  leaflets . The most stable configuration of a phospholipid bilayer is a closed  spherical shell.
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