L25 - Figure 4-38a Essential Cell Biology(© Garland...

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Figure 19-1 Essential Cell Biology (© Garland Science 2010) Bacterial Cell Division Is Relatively Simple
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Figure 18-2 Essential Cell Biology (© Garland Science 2010) The Eukaryotic Cell Cycle Has Four Phases
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Many Things Change During Mammalian M Phase 1. The cell has become rounded, and actin has formed a central ring with myosin. 1. The centrosome has divided to form the spindle poles, and microtubules have reorganized to form the mitotic spindle. 1. The chromosomes have condensed and transcription has stopped. 1. The nuclear envelope has broken down, giving the microtubules access to the chromosomes. 1. The Golgi apparatus has fragmented and secretion has stopped.
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Figure 18-24 Essential Cell Biology (© Garland Science 2010) Microtubules Bind to Chromosomes at Kinetochores
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Figure 18-25a Essential Cell Biology (© Garland Science 2010) The Mitotic Spindle Has Three Types of Microtubules
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Figure 18-30 Essential Cell Biology (© Garland Science 2010) The Spindle Poles Separate While the Chromosomes Segregate
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The Cell Cycle Can Be Arrested at Various Checkpoints Becker et al., The World of the Cell
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Unformatted text preview: Figure 4-38a Essential Cell Biology (© Garland Science 2010) Kinases and Phosphatases Control the Cell Cycle Why do you think the cell uses protein phosphorylation and dephosphorylation to control the cell cycle, rather than synthesizing and degrading whole proteins? A) These modifications are fast and readily reversible. B) Kinase and phosphatase signals are easily amplified. C) Multiple phosphorylation sites allow fine-tuning of a protein’s activity. D) It’s a trick question--in some cases, the cell does synthesize and degrade proteins to control the cell cycle. Figure 18-7 Essential Cell Biology (© Garland Science 2010) Oocyte Injection Provided an Assay for MPF Activity Figure 18-4 Essential Cell Biology (© Garland Science 2010) MPF Consists of a Cyclin Plus a Cyclin-Dependent Kinase Figure 18-18 Essential Cell Biology (© Garland Science 2010) MPF Activates Itself in a Positive Feedback Loop Figure 18-10 Essential Cell Biology (© Garland Science 2010) Multiple Cdks and Cyclins Act During the Cell Cycle...
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