L26 - Figure 16-17 Essential Cell Biology(© Garland...

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Figure 16-9 Essential Cell Biology (© Garland Science 2010) Steroid Hormomes Can Diffuse Across Cellular Membranes
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Becker et al., The World of the Cell Steroid Hormones Bind to Intracellular Receptors
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Generalizations About Signal Transduction For a given signal molecule and its receptor, the initial response is very similar in different cell types. But each cell type has a specific downstream response to activation of that receptor. For related signal molecules, the signal transduction mechanisms are often very similar, but the specific responses differ. Basic signal transduction mechanisms are conserved from yeast to fruit flies to humans.
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Figure 16-30 Essential Cell Biology (© Garland Science 2010) Receptor Tyrosine Kinases Are Activated by Dimerization
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Figure 16-31 Essential Cell Biology (© Garland Science 2010) Phosophotyrosines Activate Downstream Signal Transducers
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Figure 16-32 Essential Cell Biology (© Garland Science 2010) Receptor Tyrosine Kinases Activate a MAP Kinase Cascade
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Becker et al., The World of the Cell G Protein-Linked Receptors Are a Huge Protein Family
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Unformatted text preview: Figure 16-17 Essential Cell Biology (© Garland Science 2010) Receptor Activation Triggers G Protein Activation Figure 16-20 Essential Cell Biology (© Garland Science 2010) Activated G Proteins Generate “Second Messengers” Becker et al., The World of the Cell PIP 2 Cleavage Generates Two Second Messengers PIP 2 is membrane-associated. What about its cleavage products--will they be soluble or membrane-associated? A) Both products will be membrane-associated. B) Both products will be soluble. C) Diacylglycerol will be soluble while IP 3 will be membrane-associated. D) Diacylglycerol will be membrane-associated while IP 3 will be soluble. Figure 16-25 Essential Cell Biology (© Garland Science 2010) PIP 2 Cleavage Activates Protein Kinase C and Releases Ca 2+ Figure 16-21 Essential Cell Biology (© Garland Science 2010) Cyclic AMP (cAMP) Is a Common Second Messenger Figure 16-24 Essential Cell Biology (© Garland Science 2010) Cyclic AMP Activates Protein Kinase A...
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L26 - Figure 16-17 Essential Cell Biology(© Garland...

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