05-ReceptorsS10b

05-ReceptorsS10b - Cell receptors Lecture 05/Chapter 9 Cell...

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Cell receptors Lecture 05/Chapter 9
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2 Cell Communication Cells must interact with their environment Cells in multicellular organisms must coordinate activities Act as a single unit: a tissue or an organ Communication between cells requires: Ligand: Receptor protein: Ligand-receptor binding conveys information Causes a response through signal transduction
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Cell communication 3 Cell communication starts with ligand binding to a receptor
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4 Four mechanisms There are four basic mechanisms for cellular communication: 1. Direct contact 2. Paracrine signaling 3. Endocrine signaling 4. Synaptic signaling
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Direct contact Direct contact: molecules on the surface of one cell are recognized by receptors on adjacent cells 5 See also Figure 9.2
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Paracrine signaling Paracrine signaling: Ligands travel through the extracellular fluid 6 Figure 9.2
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Endocrine signaling Endocrine signaling: hormones released from a cell affect other cells throughout the body 7 Figure 9.2
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Synaptic signaling Synaptic signaling: nerve cells release the signal (neurotransmitter) which binds to receptors on nearby cells 8 Figure 9.2
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9 Signal transduction Receptor/ligand binding initiates a cellular response Signal transduction: Different cell types can respond differently to the same signal
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10 Cellular responses
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This note was uploaded on 02/11/2011 for the course BIO 111 taught by Professor Dr. bos during the Spring '10 term at Purdue.

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05-ReceptorsS10b - Cell receptors Lecture 05/Chapter 9 Cell...

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