Unformatted text preview: can interact with a receptor. • Recognize common features of a drug and the endogenous agent. Lecture 23 READING: same as above . Understand These Concepts: • The difference between forward chemical genetics and reverse chemical genetics approaches to drug discovery. • That drugs need to have a specific range of properties in order to be effective. • The key considerations for drugs, including size, the number of H-bond interactions, and hydrophobicity (as measured by the partition coefficient)...
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- Fall '02
- Pharmacology, Receptor antagonist, Inverse agonist