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Chapter3Transporters0

Chapter3Transporters0 - Lecture 6 Structures Transporters...

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Lecture 6 - Structures Transporters
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Learning Objectives Understand the difference between passive transport and active transport. Understand the difference between primary (ATP) and secondary (PMF) active transport. Explain why passive transport requires energy, but cannot concentrate a molecule against its gradient. Understand what part of the PMF is used by uniports to concentrate a molecule against a gradient. Differentiate between symports and antiports. Explain how symports and antiports can use both the pH and the ∆Ψ to concentrate a molecule against its gradient. Understand how the carefully regulated movement of protein structures is critical for protein function. Explain the rocker-switch mechanism for the function of MFS-type transporters. Explain the mechanism for the action of ABC importers that use a periplasmic binding protein, and explain why such transporters are essentially irreversible. Understand why PTS import of sugars is more efficient than import via other transporters. Describe the three basic categories of export transporters: - export through both membranes simultaneously
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