Chapter7Regulation

Chapter7Regulation - Lecture 16 Genetics Gene Regulation...

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Lecture 16 – Genetics Gene Regulation
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Learning Objectives Understand what it means to say a gene is “turned off” or “turned on.” List four ways a cell can make different amounts of protein from the same gene. Describe the operon concept of gene organization, and know why it only applies to prokaryotes. Distinguish between a positive control system and a negative control system. Sketch an operon controlled by an activator protein. Sketch an operon controlled by a repressor protein. Explain the difference between a constitutive gene, an inducible gene and a repressible gene. State examples of inducible genes, repressible genes and constitutive genes. Explain and sketch a diagram to show how induction and repression can act in positive control systems (controlled by activator proteins). Be able to use the lac operon as an example of induction with positive control. Explain and sketch a diagram to show how induction and repression can act in negative control systems (controlled by repressor proteins). Be able to use the lac operon as an example of induction with negative control. Describe how bacteria can use two-component regulatory systems to sense their environment. Be able to show how quorum sensing is one use of a two-component regulatory system.
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