Handout - Gene Regulation

Handout - Gene Regulation - Gene Regulation 1. Genes code...

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Gene Regulation 1. Genes code for proteins. 2. What is the regulation of genes? Choosing when to make proteins based on when they are needed 3. Who discovered gene regulation? Jacob and Monod 4. What does it mean if a gene is “inducible” ? Default state is off (you have to induce it) The gene is turned on by the presence of an inducer 5. What does it mean if a gene is “repressible” ? The default state is on (you have to repress it) The gene is turned off by the presence of an “repressor” 6. What does it mean if a gene is “constitutive” ? The gene is always turned on 7. What kind of genes code for pathway enzymes? Structural genes 8. What kind of genes code for repressor proteins? Regulatory genes 9. Genes are transcribed when the repressor is unbound. 10. The lac operon is inducible. 11. Lactose changes the shape of the repressor which causes it to fall off the DNA strands. 12. According the answer in #11, if there is a high concentration of lactose, will the genes be transcribed? Yes For the questions 12-19 (regarding the lac operon) fill in the blanks using the words given below: B-galactose Coding Enhancer Glucose Non-coding Operator Promoter Regulating Repressor 13. RNA polymerase binds to the promoter. 14. The regulating gene codes for the repressor . 15. The repressor binds to the operator.
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16. Lactose must be present for the gene to be transcribed , 17. The lac repressor is an allosteric protein . 18. The B-galactose gene breaks down lactose. 19. The lac operon is turned off when lactose is broken down (on the repressor) to change the shape of the repressor so that it can rebind with the operator . 20.
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This note was uploaded on 02/08/2011 for the course BIO 101 taught by Professor Cantwell during the Fall '08 term at University of Tennessee.

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Handout - Gene Regulation - Gene Regulation 1. Genes code...

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