050304Translation - 1 TRANSLATION 2 TRANSLATION...

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1 TRANSLATION TRANSLATION
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TRANSLATION INTRODUCTION Protein (amino acid polymer, N terminus, C terminus Ribosomes: 30 S subunit plus 50 S subunit form functional 70 S ribosome mRNA is read 5' to 3' Initiation Codons; Stop Codons Polysomes INITIATION Initiator tRNA (N - formyl methionyl tRNA) Initiation complex ELONGATION Peptidyl transferase A, P, E sites on ribosome TERMINATION Stop codons SHINE-DALGARNO 2
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3 AMIDES ACID AMINE AMIDE MONO SUBSTITUTED DISUBSTITUTED PEPTIDE BOND PEPTIDE-AMIDE FORMED BETWEEN TWO AMINO ACIDS: ALANYL-GLYCINE
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4 5' 3' 3' 5' TRANSCRIPTION TRANSLATION UNTRANSLATED REGION 5' 3' N C CODE NOBEL HOLLEY NIRENBERG KHORANA GENE PROMOTER +1 [STOP CODONS = UAA/UAG/UGA]
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5 RIBOSOMES NON-SPECIFIC TRANSLATE ANY MESSAGE PROKARYOTIC 70S 50S + 30S SUBUNITS COMPOSITION 50S 30S NUMBER OF DIFFERENT PROTEINS 34 21 NUMBER OF DIFFERENT rRNA MOLECULES ONE - 5S ONE - 23S ONE 16S POLYSOMES
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TRANSFER RNA tRNA ~ 60 EACH SPECIFIC FOR 1 AMINO ACID AND 1 CODON CODON FOR PHENYLALANINE ANTICODON
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This note was uploaded on 02/08/2011 for the course BIO 326R taught by Professor Whiteley during the Spring '08 term at University of Texas at Austin.

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050304Translation - 1 TRANSLATION 2 TRANSLATION...

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