growth_control_chemo - 1 GROWTH, CONTROL, GROWTH,...

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1 GROWTH, CONTROL, GROWTH, CONTROL, CHEMOTHERAPY CHEMOTHERAPY
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2 GROWTH, CONTROL, CHEMOTHERAPY GROWTH - Binary Fission, Growth Rate, Generation Time, N = N o 2 n Growth Phases of Culture - Lag, Exponential, Stationary, Death Physical Factors- Temperature: psychrophile, mesophile, thermophile, hyperthermophile pH, Buffer, acidophile, alkalophile Osmotic Pressure, halophile Oxygen, Aerobic, Anaerobic CONTROL OF MICROBIAL GROWTH Sterilization by Heat, Pasteurization Sterilization by Filtration Antimicrobial Agents- bacteriocidal, bacteriostatic Disinfectants, Antiseptics CHEMOTHERAPEUTIC AGENTS Ehrlich - Salvarsan - Selective Toxicity Domagk - Sulfonamides - Sulfa Drugs Sulfanailamide - para-Aminobenzoic Acid - Folic Acid Synthesis Inhibitor Fleming- Penicillin - Peptidoglycan Synthesis Inhibitor Penicillium notatum Waksman- Streptomycin, Streptomyces griseus Mycobacterium tuberculosis Protein synthesis inhibitor (70S ribosomes) Antiviral Agents Azidothymidine (AZT) - antiretroviral agent Interferon - species-specific antiviral protein
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OXYGEN 3 AEROBIC - O 2 TERMINAL ELECTRON ACCEPTOR ANAEROBIC - SOMETHING OTHER THAN O 2 OBLIGATE AEROBIC - REQUIRE O 2 ex, PSEUDOMONAS AERUGINOSA MICROAEROPHILIC - REQUIRE O 2 ; BUT IN LOW CONCENTRATION ex, NEISSERIA GONORRHOEAE FACULTATIVE ANAEROBIC - GROW WITH OR WITHOUT O 2 ; BETTER WITH O 2 ex, ESCHERICHIA COLI AEROTOLERANT ANAEROBIC - GROW EQUALLY WELL WITH OR WITHOUT O 2 ex, ENTEROCOCCUS FECALIS OBLIGATE ANAEROBIC - CANNOT GROW IN O 2 ex, CLOSTRIDIUM TETANI
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4 TEMPERATURE GROWTH RATE P S Y C H R O I L E M T LE - ºC
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pH = -log 10 [H + ]
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This note was uploaded on 02/08/2011 for the course BIO 326R taught by Professor Whiteley during the Spring '08 term at University of Texas at Austin.

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growth_control_chemo - 1 GROWTH, CONTROL, GROWTH,...

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