METABOLISMpartsB-C - METABOLISM METABOLISM parts B & C...

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METABOLISM METABOLISM parts B & C
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2 METABOLISM - PART B RESPIRATION - Aerobic, terminal electron acceptor is O 2 ELECTRON TRANSPORT CHAIN (SYSTEM) - Accept electrons from electron donors and transfer to acceptors Energy released during electron transfer used for ATP synthesis CHEMIOSMOSIS - PROTON MOTIVE FORCE pH Gradient; H + and OH - membrane bound H + ATPase; ADP + Pi form ATP (reversible) TRICARBOXYLIC ACID CYCLE Pyruvate, coenzyme A, acetyl CoA NAD + conversion to NADH + H + FAD/FADH 2 CO 2 METABOLISM - PART C MODES OF ENERGY GENERATION Aerobic respiration, Anaerobic respiration Chemolithotrophic metabolism Phototrophic metabolism ANABOLISM - BIOSYNTHESIS Low Molecular Weight Building Blocks (Precursors of Macromolecules) Twelve key, central metabolites Pentoses Amino Acids - Alanine (from Pyruvate) Tryptophan (from Phosphoenolpyruvate and erythrose-4-phosphate)
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3 AEROBIC RESPIRATION PYRUVATE NADH + H + NAD + CoA CO 2 CoA 4 OXALO- ACETATE CITRIC ACID (C 6 )
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5 ENERGY YIELD FROM PYRUVATE OXIDATION 1 PYRUVATE 3 CO 2 1 NAD + + 12 ATP 1 FAD 1 FADH 2 2 ATP 1 GDP + 1 Pi 1 GTP 1 ATP 15 ATP EQUIVALENT TO
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This note was uploaded on 02/08/2011 for the course BIO 326R taught by Professor Whiteley during the Spring '08 term at University of Texas at Austin.

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METABOLISMpartsB-C - METABOLISM METABOLISM parts B & C...

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