2008SecBvAKEY

2008SecBvAKEY - BIO 97 FINAL EXAM 2008 Section B Version BA...

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1 BIO 97 FINAL EXAM Version BA 2008 Section B Name _____________________________ID#_ _____________ Multiple Choice Section 1pt each 1 What version of the exam do you have? A. BA B. C. D. 2 Ichthyosis is an X-linked recessive disease. The frequency of Ichthyosis in females is 1/625. What is the frequency of Ichthyosis in males? A. 0.004 (1/250) B. 0.002 (1/500) C. 0.02 (1/50) D. 0.04 (1/25) E. 0.25 (1/4) D 3 Pair-rule genes influence the development of alternate segments in the embryo. These genes encode: A. Morphogens B. Transcription factors C. Gap proteins D. Oncogenes E. Egg-polarity proteins B 4 When patches of cells in the cellular blastoderm are destroyed, this results in localized defects in the larva and adult. This is because: A. bicoid mRNA is localized to the anterior. B. Morphogens determine the major axes of embryo development. C. There are too few cells to generate a complete adult animal. D. Cells are already determined by this stage. E. Homeotic genes are active at this stage. D 5 Base substitutions in coding regions that result in changed amino acids are called A. Conditional mutations B. Permissive mutations C. Missense mutations D. Nonsense mutations
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2 E. Silent mutations C 6 In the flower ABC model, A genes promote sepal formation, A and B genes promote petal formation, B and C genes promote stamen formation and C genes alone promote carpel formation. With this in mind, in mutants lacking B and C genes, you would expect that the flowers would contain: A. only sepals B. only sepals and petals C. only carpels D. no whorls E. no sepals A 7 The pedigree shows the inheritance of albinism, a homozygous recessive condition resulting in a total lack of pigment. A and a indicate dominant and recessive alleles, respectively. Solid figures represent albino individuals. What is the genotype of A-1? What is the genotype of B-1? GENOTYPE A-1 GENOTYPE B-1 A AA AA or Aa B AA Aa or AA C Aa Aa D Aa AA or Aa E Aa aa C 8 Ionizing radiation damages DNA by A. Directly interacting with the DNA molecule B. Interacting with water to form reactive ions called free radicals C. Causing DNA deamination D. By adding bulky side groups to DNA E. Promoting replication slippage B 9 In a family where one parent is heterozygous for a rare recessive trait, what is the
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3 probability that their son will have the homozygous recessive phenotype? A. 0 B. 1 C. 1/2 D. 1/4 E. 3/4 A 10 In the following scenarios, if the mutation arose in somatic tissues, would you expect it to be tumor promoting? Each question is independent of the other two. I. An amplification of the gene region that contains p53. II. A nonsense mutation that occurs shortly after the beginning of translation in a gene encoding the antiapoptotic protein, Bcl-2. III.
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2008SecBvAKEY - BIO 97 FINAL EXAM 2008 Section B Version BA...

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